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Using the drop-down menu below, read about highlighted scientific news from ASCO's Annual Meetings since 2002. You can select a specific year and/or a specific topic, such as a type of cancer. Selecting "All" will take you to a complete list of articles that appear under all categories.
The 2013 ASCO Annual Meeting was held May 31-June 4, with research news released starting May 15. The 2014 event will be held May 30-June 3.
To read these summaries categorized into a yearly newsletter, you can also review Cancer Advances: News for Patients from the ASCO Annual Meeting.
Don’t forget to check out audio podcasts and videos about this news, as well. And, in addition to the highlighted studies below, thousands of scientific abstracts are released each year at the ASCO Annual Meeting. To search the entire collection of meeting abstracts, visit ASCO's website.
A new study showed that the targeted drug regorafenib is an effective treatment for patients with gastrointestinal stromal tumor (GIST) that has worsened because the other available treatments have stopped working. Targeted therapy is a treatment that targets a tumor's specific genes, proteins, or the tissue environment that contributes to cancer growth and survival. Specifically, regorafenib targets an abnormal enzyme called KIT. The currently available GIST treatments, imatinib (Gleevec) and sunitinib (Sutent), often slow or stop tumor growth at first, but eventually the drugs stop working and the cancer continues to grow. Regorafenib appears to work in a different way, even helping to slow GIST growth when other treatments are no longer working.
A study on the drug imatinib (Gleevec) for patients with high-risk gastrointestinal stromal tumor (GIST) showed that three years of treatment after surgery helped patients live longer and avoid recurrences (cancer that comes back after treatment). Imatinib is a type of targeted therapy, a treatment that targets the cancer's specific genes, proteins, or the tissue environment that contributes to cancer growth and survival. Specifically, it targets gene mutations (changes) that contribute to cancer growth for about 90% of people with GIST. The current standard treatment for GIST that can be surgically removed is one year of imatinib after surgery.
A new drug called SU11248 shrinks or slows the progression of cancer in patients with gastrointestinal stromal tumor (GIST) whose tumors have stopped responding to the standard treatment of imatinib (Gleevec). However, imatinib eventually stops working in about half of all patients, and the cancer progresses.