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Research Summaries
Using the drop-down menu below, read about highlighted scientific news from ASCO's Annual Meetings since 2002. You can select a specific year and/or a specific topic, such as a type of cancer. Selecting "All" will take you to a complete list of articles that appear under all categories.
The 2013 ASCO Annual Meeting is set for May 31-June 4, with research news beginning to be released on May 15 at 6pm Eastern. Additional research will be released each day of the meeting.
To read these summaries categorized into a yearly newsletter, you can also review Cancer Advances: News for Patients from the ASCO Annual Meeting.
Don’t forget to check out audio podcasts and videos about this news, as well. And, in addition to the highlighted studies below, thousands of scientific abstracts are released each year at the ASCO Annual Meeting. To search the entire collection of meeting abstracts, visit ASCO's website.
According to a recent study, giving bevacizumab (Avastin) along with standard chemotherapy doubled the time it took for platinum-resistant ovarian, fallopian tube, and primary peritoneal cancers to worsen. These are all cancers of a woman's reproductive system that are treated similarly. Platinum-based chemotherapy is often the first treatment for these cancers and includes the drugs cisplatin (Platinol), carboplatin (Paraplat, Paraplatin), and oxaliplatin (Eloxatin). When platinum-based drugs stop working to control the cancer's growth, it is called platinum-resistant cancer.
In two recent studies, researchers looked at the drug bevacizumab (Avastin) to treat recurrent and newly-diagnosed ovarian cancer. Bevacizumab is a type of targeted therapy, a treatment that targets the cancer's specific genes, proteins, or the tissue environment that contributes to cancer growth and survival.
A large study evaluating ovarian cancer screening showed that using both a CA-125 blood test and transvaginal ultrasound to find early ovarian cancer did not reduce the risk of dying from the disease and resulted in unnecessary follow-up procedures. The CA-125 blood test measures the amount of a tumor marker called CA-125, which may be found in higher levels in women with ovarian cancer. A transvaginal ultrasound uses sound waves to create pictures of the ovaries. Both tests are used to evaluate the symptoms of ovarian cancer, its stage, and the effectiveness of treatment.
In a recent study, the drug cabozantinib helped manage various advanced cancers, particularly prostate, ovarian, and liver cancers. The drug also helped shrink bone metastases (cancer that has spread to the bone). Cabozantinib is a type of targeted therapy, which means it targets the cancer's specific genes, proteins, or the tissue environment that contributes to cancer growth and survival.
In a recent study, researchers found that maintenance therapy with olaparib, a type of drug called a PARP inhibitor, increased the amount of time it took for recurrent ovarian cancer (cancer that has come back after treatment) to worsen. Maintenance therapy is ongoing treatment that is given after the standard treatment to help control the growth of cancer.
According to a new study, adding the targeted therapy drug bevacizumab (Avastin) to chemotherapy and keeping patients on the drug after chemotherapy ends increases the amount of time it takes for advanced epithelial ovarian cancer, primary peritoneal cancer, and Fallopian tube cancer to grow and spread. These are all cancers of a woman's reproductive system that are treated similarly.
Researchers have developed a way to screen women who don't have a high risk of ovarian cancer and who have been through menopause. There are currently no screening methods for women who don't have a high risk of ovarian cancer. Women at high risk for ovarian cancer may receive regular screening or reduce their risk of cancer in other ways, such as surgery to remove the ovaries. This new method estimates a woman's risk of ovarian cancer by using her age and the results of a yearly CA-125 blood test. CA-125 is a substance called a tumor marker that is found in higher levels in women with ovarian cancer. In this study, women who had increasing CA-125 levels received transvaginal sonography (TVS), an imaging test that uses sound waves to create a picture of the ovaries and look for any tumors, and were referred to a gynecologic oncologist to decide if surgery was needed. A gynecologic oncologist is a doctor who specializes in treating cancer in a woman's reproductive organs.
Recent research compared treatments for locally advanced cervical cancer and the effect of different lymph node (tiny, bean-shaped organs that help fight infection) removal techniques for early-stage cervical cancer. Another study looked at when to start treatment for ovarian cancer recurrence. In addition, a national survey provided information about discussing fertility preservation.
