Gastrointestinal Stromal Tumor - GIST: Latest Research

This section has been reviewed and approved by the Cancer.Net Editorial Board, 11/2013

ON THIS PAGE: You will read about the scientific research being done now to learn more about this type of tumor and how to treat it. To see other pages, use the menu on the side of your screen.

Doctors are working to learn more about GIST, ways to prevent it, how to best treat it, and how to provide the best care to people diagnosed with this disease. The following areas of research may include new options for patients through clinical trials. Always talk with your doctor about the diagnostic and treatment options best for you.

New drugs. Research continues to find new drugs for GIST, particularly new targeted therapies that may work either alone or in combination with existing drugs such as imatinib. Several different drugs that target proteins that help tumor cells survive have recently been or are being researched, including olaratumab (IMC-3G3), crenolanib (ARO-002 or CP-868,596), linsitinib (OSI-906), and heat shock protein 90 (HSP90) inhibitors.

Supportive care. Clinical trials are underway to find better ways of reducing symptoms and side effects of current treatments for GIST in order to improve patients’ comfort and quality of life.

Looking for More about Latest Research?

If you would like additional information about the latest areas of research regarding GIST, explore these related items that take you outside of this guide:

The next section addresses how to cope with the symptoms of the disease or the side effects of its treatment. Use the menu on the side of your screen to select Coping with Side Effects, or you can select another section, to continue reading this guide.