Gestational Trophoblastic Tumor: Latest Research

This section has been reviewed and approved by the Cancer.Net Editorial Board, 01/2012

ON THIS PAGE: You will read about the scientific research being done now to learn more about this type of cancer and how to treat it. To see other pages, use the menu on the side of your screen.

Doctors are working to learn more about gynecologic cancer (cancer of a woman's reproductive system), ways to prevent it, how to best treat it, and how to provide the best care to women diagnosed with this disease. The following areas of research may include new options for patients through clinical trials. Because GTTs are uncommon, GTT-only clinical trials may be hard to find. However, there are several clinical trials that are open to people with different types of cancer, particularly other gynecologic cancers, that include GTT. Always talk with your doctor about the diagnostic and treatment options best for you.

New drug therapies. Researchers are studying new drugs for the treatment of GTTs and gynecologic cancers, including targeted therapies. New drugs that impair various processes in the cancer cell, including topoisomerase-I inhibitors (drugs that interfere with the replication of DNA, which affects cancer cell growth), angiogenesis inhibitors (drugs that stop the formation of blood vessels needed for the tumor to grow and spread), and microtubule agents (drugs that disrupt the structure of cancer cells), are being tested to treat GTTs. In addition, researchers are also studying the use of growth factors added to chemotherapy.

New treatment combinations. Doctors continue to evaluate different combinations of current treatment options, as well as integrating new approaches under study in clinical trials.

Stem cell transplantation. A stem cell transplant is a medical procedure in which diseased bone marrow is replaced by highly specialized cells, called hematopoietic stem cells. Early studies are underway to determine if transplantation is effective for advanced GTT. Learn more about stem cell transplantation.

Supportive care. Clinical trials are underway to find better ways of reducing symptoms and side effects of current treatments for GTT in order to improve patients' comfort and quality of life.

Learn more about common statistical terms used in cancer research.

To find clinical trials specific to your diagnosis, talk with your doctor or search online clinical trial databases now.

The next section addresses how to cope with the symptoms of the disease or the side effects of its treatment. Use the menu on the side of your screen to select Coping with Side Effects, or you can select another section, to continue reading this guide.