Lymphoma - Non-Hodgkin - Childhood: Latest Research

Approved by the Cancer.Net Editorial Board, 08/2015

ON THIS PAGE: You will read about the scientific research being done now to learn more about this type of cancer and how to treat it. To see other pages, use the menu on the side of your screen.

Doctors are working to learn more about childhood NHL, ways to prevent it, how to best treat it, and how to provide the best care to people diagnosed with this disease. The following areas of research may include new options for patients through clinical trials. Always talk with your child’s doctor about the diagnostic and treatment options best for your child.

  • Genetics. One of the most important areas of research involves learning more about the genetic predisposition to developing childhood NHL and about how well genetic subtypes of NHL will respond to different treatments.

  • Immunotherapy. As explained in the Treatment Options section, immunotherapy (also called biologic therapy) is designed to boost the body’s natural defenses to fight the cancer. Research for NHL is investigating the use of monoclonal antibodies designed to kill lymphoma cells that make a specific protein and spare normal cells from the toxic effects of chemotherapy.

  • Targeted therapy. Targeted therapy is a treatment that targets the cancer’s specific genes, proteins, or the tissue environment that contributes to cancer growth and survival. For NHL, researchers are investigating specific drugs that affect the regulation of the lymphoma cell, while limiting damage to normal cells. Learn more about targeted treatments.

  • Expanded use of stem cell transplantation. Other research involves reduced intensity conditioning therapy (lower doses of chemotherapy and radiation therapy, aiming to reduce complications following a transplantation) followed by allogeneic stem cell transplantation for children with recurrent NHL.

  • Palliative care. Clinical trials are underway to find better ways of reducing symptoms and side effects of current NHL treatments in order to improve patients’ comfort and quality of life.

Looking for More About Latest Research?

If you would like additional information about the latest areas of research regarding NHL, explore these related items that take you outside of this guide:

  • To find clinical trials specific to your diagnosis, talk with your child’s doctor or search online clinical trial databases now.

  • Visit ASCO’s CancerProgress.Net website to learn more about the historical pace of research for childhood cancer.

  • Visit the website of the Conquer Cancer Foundation to find out how to help support research for every cancer type. Please note this link takes you to a separate ASCO website. 

The next section in this guide is Coping with Side Effects and it offers some guidance in how to cope with the physical, emotional, and social changes that NHL and its treatment can bring. Or, use the menu on the side of your screen to choose another section to continue reading this guide.