Skin Cancer (Non-Melanoma): Latest Research

Approved by the Cancer.Net Editorial Board, 06/2015

ON THIS PAGE: You will read about the scientific research being done now to learn more about non-melanoma skin cancer and how to treat it. To see other pages, use the menu on the side of your screen.

Doctors are working to learn more about skin cancer, ways to prevent it, how to best treat it, and how to provide the best care to people diagnosed with this disease. The following areas of research may include new options for patients through clinical trials. Always talk with your doctor about the diagnostic and treatment options best for you.

  • EGFR inhibitors for advanced or metastatic squamous cell carcinoma. Many squamous cell carcinomas grow uncontrollably because of a tumor protein known as the epidermal growth factor receptor (EGFR). Several clinical trials are investigating whether combining drugs that inhibit EGFR with radiation therapy is an effective treatment option for advanced or metastatic disease.

  • Additional Hedgehog pathway inhibitors for advanced basal cell carcinoma. Researchers are developing new hedgehog pathway inhibitors for advanced basal cell carcinoma that cannot be treated with surgery or radiation therapy.

  • Combining Hedgehog pathway inhibitors with other therapies. Researchers are testing whether combining hedgehog inhibitors with other treatments, such as surgery and radiation therapy, would be beneficial for basal cell carcinomas that are difficult to cure.

  • Palliative care. Clinical trials are underway to find better ways of reducing symptoms and side effects of current skin cancer treatments, in order to improve patients’ comfort and quality of life.

Looking for More About the Latest Research?

If you would like additional information about the latest areas of research regarding non-melanoma skin cancer, explore these related items that take you outside of this guide:

The next section in this guide is Coping with Side Effects, and it offers some guidance in how to cope with the physical, emotional, and social changes that cancer and its treatment can bring. Or, use the menu on the side of your screen to choose another section to continue reading this guide.