ASCO Medical Journals

Obesity Linked to Shorter Survival after Diagnosis of Pancreatic Cancer

JCO Research Round Up
October 21, 2013

A large, long-term follow-up study showed that people who were overweight or obese years before their pancreatic cancer diagnosis tend to have more advanced stage at diagnosis and shorter survival.  Prior research had suggested that having a higher body mass index (BMI) increases one’s risk of developing pancreatic cancer. This is the first prospective study to demonstrate that BMI also affects outcomes after diagnosis.

Patients with Lung Cancer Harboring a Rare HER2 Alteration May Benefit from anti-HER2 Therapy

JCO Research Round Up
April 22, 2013

New findings from a retrospective study suggest that targeted anti-HER2 therapy may slow disease progression in patients with advanced lung cancer who carry a specific alteration in HER2—a protein that controls cancer growth and spread, found on some cancer cells, such as breast, ovarian, and lung cancer cells.

Cetuximab Added to Chemotherapy Helps Some Patients With Advanced Colorectal Cancer That Has Spread to the Liver Live Longer

JCO Research Round Up
April 8, 2013

New findings from a clinical trial in patients with colorectal cancer and inoperable metastases in the liver (cancer that has spread from the colon or rectum to the liver) suggest that combination treatment with standard therapy and targeted drug cetuximab (Erbitux) caused significant shrinkage of metastases, making successful surgery feasible. Patients who received cetuximab in addition to traditional chemotherapy lived markedly longer than those who received only chemotherapy. 

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