ASCO Medical Journals

Large Study Shows Progressive Increases in Long-Term Survival for Children With Leukemia

JCO Research Round Up
March 12, 2012

A new, long-term study shows that survival rates for children and adolescents with acute lymphoblastic leukemia (ALL), the most common type of pediatric cancer, climbed steadily between 1990 and 2005. This analysis is the largest study to date of ALL survival, exploring important survival gains based on patient age, race, ethnicity, and subtype of ALL. The findings were published March 12 in the Journal of Clinical Oncology.

New Analysis Provides Clearer Picture of Cancer Risks Associated With Lynch Syndrome

JCO Research Round Up
February 13, 2012

Lynch syndrome is an inherited condition of cancer predisposition caused by mutations in certain genes involved in repairing DNA damage, called “mismatch repair” genes. A new study published in the Journal of Clinical Oncology provides a new, clearer picture of the cancer risks that carriers of these mutations face, which could ultimately help guide future screening efforts to detect these cancers at an early stage.

Study Shows No Increased Risk of Breast Cancer for Non-Carriers in Families with BRCA Gene Mutation

JCO Research Round Up
October 31, 2011

An analysis of more than 3,000 families including women with breast cancer has found that close relatives of women who carry mutations in a BRCA gene - but who themselves do not have such genetic mutations - do not have an increased risk of developing breast cancer compared to relatives of women with breast cancer who do not have such mutations.

Using MRI to Measure Tumor Shrinkage Predicts Survival in Advanced Rectal Cancer

JCO Research Round Up
August 29, 2011

A new study has shown that for patients with advanced rectal cancer, using magnetic resonance imaging (MRI) to assess their tumor's response to pre-surgery chemotherapy or radiation treatment may predict survival. The findings suggest that by using MRI to gauge whether a tumor has responded to such treatments, physicians can use the results to determine whether to proceed with surgery or to consider other treatment options for a given patient. 


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