Breast Cancer

Calculating a Recurrence Score Helps Predict Survival for Patients With Breast Cancer That Has Spread to the Lymph Nodes

Breast Cancer Symposium
September 11, 2012

Using a specialized 21-gene test of a breast tumor’s genes, researchers found that the result, called a Recurrence Score (RS), predicted the prognosis (chance of recovery) for patients with estrogen-receptor positive breast cancer that has spread to the axillary (underarm) lymph nodes. Previous studies have shown that these 21 genes help predict the risk of recurrence (cancer that comes back after treatment) and the risk of death from cancer for women with breast cancer that has not spread to the axillary lymph nodes.

Newer, More Costly Drugs No Better Than Standard Chemotherapy for Breast Cancer

ASCO Annual Meeting
June 4, 2012

Giving either of two newer and more costly drugs, nanoparticle albumin-bound paclitaxel (Abraxane; called nab-paclitaxel) and ixabepilone (Ixempra), did not work better to treat locally advanced or metastatic breast cancer than standard chemotherapy with paclitaxel, according to a large study. Locally advanced breast cancer is cancer that has spread to parts of the body near the breast. Metastatic breast cancer has spread to other, more distant parts of the body.

Study Shows No Increased Risk of Breast Cancer for Non-Carriers in Families with BRCA Gene Mutation

JCO Research Round Up
October 31, 2011

An analysis of more than 3,000 families including women with breast cancer has found that close relatives of women who carry mutations in a BRCA gene - but who themselves do not have such genetic mutations - do not have an increased risk of developing breast cancer compared to relatives of women with breast cancer who do not have such mutations.


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