Lung Cancer

Second-Line Treatment with Ramucirumab and Chemotherapy Lengthens Lives of Patients with NSCLC

ASCO Annual Meeting
May 31, 2014

Results from a new study show that combining the targeted therapy ramucirumab (Cyramza) with standard chemotherapy lengthens the lives of patients with non-small cell lung cancer (NSCLC). Targeted therapy is a treatment that targets the cancer’s specific genes, proteins, or the tissue environment that contributes to cancer growth and survival. Specifically, ramucirumab targets a protein called VEGF receptor 2, blocking the growth of new blood vessels in the tumor that are needed for the tumor to grow and spread.

Early Results Suggest New EGFR Targeted Therapy Shrinks Worsening Lung Cancers with Fewer Side Effects

ASCO Annual Meeting
May 14, 2014

In a recent phase I clinical trial, about 50% of patients receiving a new targeted therapy for worsening non-small cell lung cancer (NSCLC) had the cancer shrink. Targeted therapy is a treatment that targets the cancer’s specific genes, proteins, or the tissue environment that contributes to cancer growth and survival. Specifically, this new targeted therapy, AZD9291, targets changes or mutations to the epidermal growth factor receptor (EGFR).

Patients with Lung Cancer Harboring a Rare HER2 Alteration May Benefit from anti-HER2 Therapy

JCO Research Round Up
April 22, 2013

New findings from a retrospective study suggest that targeted anti-HER2 therapy may slow disease progression in patients with advanced lung cancer who carry a specific alteration in HER2—a protein that controls cancer growth and spread, found on some cancer cells, such as breast, ovarian, and lung cancer cells.

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