Consumption of Citrus Fruit May be Associated With Increased Risk for Melanoma, but More Research is Needed

Journal of Clinical Oncology
June 29, 2015 

A prospective study of more than 100,000 Americans suggests that consuming citrus fruit, specifically whole grapefruit and orange juice, frequently may increase one’s chance of developing melanoma. However, experts stress more research is needed and caution against making any dietary changes based on this study at this time.

Nivolumab Slows Melanoma Growth Better than just Ipilimumab

ASCO Annual Meeting
May 31, 2015

Recently, researchers found that nivolumab (Opdivo) either given as a single treatment or in combination with ipilimumab (Yervoy) is more effective than treatment with ipilimumab alone for people with advanced melanoma. Both nivolumab and ipilimumab are types of immunotherapy that block two proteins called PD-1 and CTLA-4. By blocking these two proteins, the drugs are able to boost the body’s immune system to fight the cancer. 

Some People with Melanoma May Not Need Extensive Lymph Node Surgery

ASCO Annual Meeting
May 30, 2015

According to the results of a recent study, people who have surgery to remove lymph nodes near a melanoma tumor live the same amount of time as those who are watched closely for signs of cancer. Lymph nodes are tiny, bean-shaped organs that fight infection. During melanoma surgery, doctors look for cancer that has spread to the lymph nodes. If melanoma is found in these lymph nodes, there is a higher risk of the cancer coming back after treatment.

New Immunotherapy, MK-3475, Shows Promise for Metastatic Melanoma

ASCO Annual Meeting
June 2, 2014

According to the results of a large phase I study, a new drug called MK-3475 may benefit people with melanoma that has spread to other parts of the body. MK-3475 blocks the function of a protein called PD-1 (programmed death-1) found on T-cells, a type of white blood cell that directly helps fight disease. Because PD-1 keeps the immune system from destroying cancer cells, stopping PD-1 from working allows the immune system to better eliminate melanoma.


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