Research Summaries

Study Shows No Increased Risk of Breast Cancer for Non-Carriers in Families with BRCA Gene Mutation

JCO Research Round Up
October 31, 2011

An analysis of more than 3,000 families including women with breast cancer has found that close relatives of women who carry mutations in a BRCA gene - but who themselves do not have such genetic mutations - do not have an increased risk of developing breast cancer compared to relatives of women with breast cancer who do not have such mutations.

Using MRI to Measure Tumor Shrinkage Predicts Survival in Advanced Rectal Cancer

JCO Research Round Up
August 29, 2011

A new study has shown that for patients with advanced rectal cancer, using magnetic resonance imaging (MRI) to assess their tumor's response to pre-surgery chemotherapy or radiation treatment may predict survival. The findings suggest that by using MRI to gauge whether a tumor has responded to such treatments, physicians can use the results to determine whether to proceed with surgery or to consider other treatment options for a given patient. 

New High-Dose Chemotherapy Regimen Helps Children With Neuroblastoma Live Longer

ASCO Annual Meeting
June 5, 2011

A recent study showed that children with high-risk neuroblastoma who received the drugs busulphan (Busulfex, Mitosan, Myleran) and melphalan (Alkeran) lived longer than children who received the drugs carboplatin (Paraplat, Paraplatin), etoposide (Toposar, VePesid), and melphalan, a regimen called CEM. High-risk means that the neuroblastoma is likely to worsen or recur (come back after treatment). These combinations of drugs are given in high doses to kill cancer cells in the bone marrow (spongy, red tissue inside of bones).

Primary Care Doctors and Medical Oncologists Have Different Concerns About Providing Survivorship Care

ASCO Annual Meeting
June 5, 2011

A survey of both primary care doctors and medical oncologists (doctors who treat cancer using medications) about the barriers to providing survivorship care showed that primary care doctors and medical oncologists have different concerns about caring for survivors.

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