Cancer-related fatigue is a persistent sense of tiredness or exhaustion from cancer or cancer treatment. People who feel fatigue often say that even a small effort, such as walking across a room, can seem like too much. Fatigue can seriously affect a person's daily activities, including the ability to work, be involved with their family, or socialize. Fatigue may cause people to avoid or skip cancer treatments and may even affect their desire to live.

It is common for fatigue to appear after treatment at the following times:

• A few days after chemotherapy treatment
  
  
• A few weeks after beginning radiation treatment
  
  
• After treatment with immunotherapy (also known as biologic therapy), such as alpha-interferon (Roferon-A, Intron A, Alferon N) and interleukins (Proleukin or Oprelvekin)

Sometimes, other conditions may contribute to fatigue, including uncontrolled pain, depression, or insomnia.

Diagnosis

It is important to tell your doctor if you are experiencing fatigue. To understand your fatigue, your doctor may ask you at what times you feel especially tired and whether the fatigue affects your ability to perform regular activities. You may even be asked to describe your fatigue on a scale from "no fatigue" to "most fatigue." Your doctor may also take a blood sample to determine whether anemia (low number of red blood cells) or another problem may be causing fatigue.

Managing fatigue

The following suggestions may help you better manage fatigue:

• Exercise regularly. People who exercise experience less fatigue overall and report improvement in appetite, weight, bowel habits, strength, and self-image. It can start with something simple, such as walking a few minutes a day.
  
  
• Conserve your energy. Choose a time of day when you have more energy for daily activities, prioritize activities, and do tougher tasks during the time of day when you have the most energy.
  
  
• Seek treatment for depression, pain, sleep disorders, or other conditions that may be adding to your fatigue.

More Information

Coping With Cancer-Related Fatigue

Anemia

Managing Side Effects

Additional Resources

Lance Armstrong Foundation: Fatigue

Cancersymptoms.org: Fatigue

Last Updated: September 28, 2009