Oncologist-approved cancer information from the American Society of Clinical Oncology

Brain and Central Nervous System Cancers

News and highlights from ASCO Annual Meetings.


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Drug Used for Sleep Disorders Improves Quality of Life for People with Brain Cancer
June 4, 2006

A new study shows for the first time that modafinil (Provigil), a drug generally used to treat sleeping disorders, improves cognitive functions (such as concentration and attention) and mood and lowers fatigue levels in patients with brain cancer.
Adding Chemotherapy to Radiation Therapy Improves Survival in Patients with GBM
June 7, 2004

Glioblastoma multiforme (GBM) is a fast-growing primary brain cancer that is difficult to treat. The standard treatment for GBM is surgery followed by radiation therapy. However, patients diagnosed with GBM usually have a poor prognosis (chance of recovery). Results of a recent, large, multi-institutional phase III clinical trial show that treating patients with radiation and chemotherapy improves both progression-free survival and overall survival in GBM.
Chemotherapy Can Delay Brain Tumor Progression; Genetic Differences in Brain Tumors Linked to Survival
June 6, 2004

Anaplastic oligodendrogliomas (AOs) and anaplastic oligoastrocytomas (AOAs) are rare but fast-growing tumors that develop in the brain. The standard treatment is surgery followed by radiation. Doctors also know that these tumors respond to a chemotherapy regimen called PCV (procarbazine, lomustine, and vincristine). This study was done to find out whether giving PCV before radiation treatment improved survival in people with AOs and AOAs.
New Tumor Marker Affects Prognosis in Glioma
June 6, 2004

Researchers have discovered a correlation between a tumor protein called epidermal growth factor receptor (EGFR) vIII ("variant three") and the prognosis (chance of recovery) of grade 3 and 4 primary brain tumors called gliomas.
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