People with an endocrine tumor may experience the following symptoms or signs. Sometimes, people with an endocrine tumor do not show any of these symptoms. Or, these symptoms may be caused by a medical condition that is not a tumor. If you are concerned about a symptom or sign on this list, please talk with your doctor.

Most symptoms of an endocrine tumor are specific to the type of tumor. For more information, see each individual tumor type [2]. The following are some common symptoms of an endocrine tumor:

• Thickening or lump in any part of the body
• Persistent pain in a specific (localized) area
• Anxiety (including panic attacks)
• Irritability
• Depression
• Confusion
• Nervousness
• Fatigue
• Fever
• Sweating
• Headaches
• Nausea
• Vomiting
• Diarrhea
• Changes in bowel or bladder habits
• Unexplained weight gain or loss
• Jaundice (yellowing of the skin and whites of the eyes)
• Facial flushing (redness and warm feeling over the face)
• Intestinal bleeding

Your doctor will ask you questions about the symptoms you are experiencing to help find out the cause of the problem, called a diagnosis [3]. This may include how long you've been experiencing the symptom(s) and how often.

If an endocrine tumor is diagnosed, relieving symptoms and side effects remains an important part of your medical care and treatment. This may also be called symptom management, palliative care, or supportive care. Be sure to talk with your health care team about symptoms you experience, including any new symptoms or a change in symptoms.