Hormone therapy for prostate cancer comes in several forms: surgical removal of the testicles, LHRH agonist drugs, anti-androgen drugs, and a combination of these treatments. Men with advanced prostate cancer should discuss with their doctors the risks and benefits of all the treatment options and when to begin treatment. This discussion should address the current state of the cancer (such as whether PSA levels are rising or steady and whether the cancer has spread to the bones), your health history, and other medical conditions, such as diabetes. You may also want to discuss any concerns you may have about how your sexual and physical functioning might be affected by hormone therapy. For some men, the side effects of prostate cancer treatment are a bigger risk to their health than the prostate cancer itself, so it is important to talk with your doctor about the long-term side effects of a particular treatment.