This section contains the latest highlighted research for patients from ASCO medical journals, including the Journal of Clinical Oncology, as well as an archive of research highlights from previous ASCO scientific meetings (2011-2015). For the latest research highlights from more recent ASCO meetings, visit the Cancer.Net Blog or check out Cancer.Net’s audio podcasts and videos for patients.
To search this archive, use the drop-down menu below. You can select a specific year, meeting or publication, and/or a specific topic, such as a type of cancer. Selecting "All" will take you to a complete list of articles that appear under all categories.
This is a transcript of a podcast led by Dr. Julia White, who discusses one study highlighted at the 2014 Breast Cancer Symposium that presents research on the impact of sending reminders to women overdue for breast cancer screening with mammography.
This is a transcript of a podcast led by Dr. Harold Burstein, who discusses one study highlighted at the 2014 Breast Cancer Symposium that presents research on the impact that Angelina Jolie’s choice of having surgery to prevent breast cancer had on genetic testing for genes linked to breast cancer risk.
This is a transcript of a podcast led by Dr. Amy Early, who discusses one study highlighted at the 2014 Breast Cancer Symposium that presents research on breast cancer recurrence after chemotherapy given before surgery.
This a transcript of a podcast led by Dr. Julie Margenthaler, who discusses two studies highlighted at the 2014 Breast Cancer Symposium that relate to surgery for breast cancer treatment and prevention.
A new study has found that using magnetic resonance imaging (MRI), in addition to mammography, before or immediately after a lumpectomy (surgical removal of the tumor and a small, cancer-free margin of tissue around the tumor) was not linked to a decrease in how often women with ductal carcinoma in situ (DCIS) of the breast experienced a local recurrence (cancer that comes back in the same area of the breast after treatment) or contralateral breast cancer (a new tumor that develops in the other breast).
A large-scale survey of Long Island women who were having mammography to screen for breast cancer shows that the majority (more than 90%) either under- or overestimated their risk of developing this disease during their lifetime. Additionally, four out of every 10 women surveyed (40%) said they had never discussed their personal breast cancer risk with a doctor.
A large study found that women who received radiation therapy to treat ductal carcinoma in situ of the breast (DCIS) had no increased risk of developing cardiovascular (heart) disease compared with the general population or patients with DCIS who only had surgery. Previous studies involving patients with breast and other cancers have shown that radiation therapy directed at areas near the heart can increase their long-term risk of developing cardiovascular disease, so these results may help women who are deciding on their treatment plan and may reassure DCIS survivors who received radiation therapy.
A new simulation study indicates that women with stage II breast cancer who have a high risk of the cancer remaining in their axillary (underarm) lymph nodes after treatment, called residual nodal disease, may benefit from having these lymph nodes removed in a procedure called an axillary lymph node dissection. Women who have more cancerous lymph nodes in the underarm generally have a higher risk of residual nodal disease. Cancer in this area is found through a sentinel lymph node biopsy. A sentinel lymph node biopsy is the removal of one or a few lymph nodes in the underarm to look for cancer cells. If cancer cells are found, additional treatment may be needed.
In a recent study, researchers found that a new device called MarginProbe helps make sure enough tissue is removed during a lumpectomy. A lumpectomy is the removal of the tumor and some of the surrounding tissue, called a margin, during an operation. Currently, surgeons often have to wait one or two weeks to find out if the tissue around the tumor that was removed during surgery contains cancer cells. Because of this, up to 40% of women who have had a lumpectomy need to have more surgeries to remove this additional cancerous tissue.
Using a specialized 21-gene test of a breast tumor’s genes, researchers found that the result, called a Recurrence Score (RS), predicted the prognosis (chance of recovery) for patients with estrogen-receptor positive breast cancer that has spread to the axillary (underarm) lymph nodes. Previous studies have shown that these 21 genes help predict the risk of recurrence (cancer that comes back after treatment) and the risk of death from cancer for women with breast cancer that has not spread to the axillary lymph nodes.