Using the drop-down menu below, read about highlighted scientific news for patients from ASCO's Annual Meetings, Symposia, and medical journals for the past three years. You can select a specific year, meeting or publication, and/or a specific topic, such as a type of cancer. Selecting "All" will take you to a complete list of articles that appear under all categories.
This includes ASCO’s Journal of Clinical Oncology and its scientific meetings, including the ASCO Annual Meeting, a five-day meeting held each May/June. To read the Annual Meeting summaries compiled into a yearly newsletter, you can also review Research Round Up: News for Patients from the ASCO Annual Meeting.Don’t forget to check out audio podcasts and videos about this news, as well. And a list of upcoming Symposia can be found here. And, in addition to the highlighted studies below, thousands of scientific abstracts are released each year at different ASCO meetings. To search the entire collection of meeting abstracts, visit ASCO's website.
Recently, researchers developed a new way to classify stage II and III colorectal cancers based on gene expression (which genes within each tumor are turned on or off) into three separate subtypes. Each of these subtypes helps predict a patient’s prognosis (chance of recovery) and how a tumor responds to adjuvant chemotherapy (chemotherapy given after treatment). Previously studied genetic tests, such as Oncotype or ColoPrint, can help doctors find out which tumors are more likely to grow and spread quickly, but there are still no clear recommendations for identifying which patients should receive adjuvant chemotherapy and which patients wouldn’t benefit from additional chemotherapy..
In a new study in Japan, researchers found that patients with pancreatic cancer lived longer when they received chemotherapy with a drug called S-1 after surgery. This study included Japanese patients with stage I, II, or III pancreatic cancer who were able to have surgery to remove the tumor. In the United States, more than half of pancreatic cancers are diagnosed after the disease has spread beyond the pancreas. Because of this, only 20% to 30% of patients with pancreatic cancer are able to have surgery. Typically, patients who are able to have surgery are offered the drug gemcitabine (Gemzar) after the surgery to help lengthen their lives. In previous studies, researchers have found that this new drug, S-1, works as well as gemcitabine for Asian patients with pancreatic cancer. However, other studies have shown that S-1 may cause more harmful side effects in patients who are not Asian.
An early ongoing study suggests that looking at gene expression (which genes within each tumor are turned on or off) may help doctors predict how well chemotherapy will work and monitor how well chemotherapy is treating the cancer. Some genes within pancreatic tumors are similar between patients and some are different. These differences affect how well cancer drugs work for each patient.
Women who have a higher risk of the cancer developing in the other breast often have at least two first-degree relatives with breast or ovarian cancer and/or have changes in BRCA1 and BRCA2 genes. In this survey, women who had those risk factors were more likely to choose CPM. However, worry about recurrence also caused women to choose CPM, as 90% of women who received CPM said they were “very worried about recurrence” compared with 80% of women who received a mastectomy for only the breast with cancer.
An analysis of information provided by oncology practices participating in the American Society of Clinical Oncology’s Quality Oncology Practice Initiative (QOPI®) showed that the practices were able to improve the quality of care provided to patients between 2006 and 2010. QOPI® is a national program designed to measure the care provided to patients so each doctor's office or treatment center that participates in the program can use that information to improve the cancer care they provide.
This study included a range of specialists who were part of the Duffey Pain and Palliative team of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University. The team of two nurses, a social worker, a palliative care doctor, a pharmacist, a nutritionist, and a chaplain help manage a patient’s symptoms and provide emotional support for patients before, during, and after hospitalization.
A large study on a new real-time performance tracking system showed that this system was able to improve the quality of care provided to patients with breast and colon cancers. Researchers also found that using this system reduced differences in cancer care related to age, race, and lack of health insurance. Developed by the Commission on Cancer of the American College of Surgeons, the Rapid Quality Reporting System (RQRS) monitors whether treatment centers adhere to five specific standards of quality care for breast and colon cancer. It uses current information on the care patients are receiving, instead of information from the past, to improve how patients are cared for in the treatment centers using RQRS.
In a recent study, researchers found that a new device called MarginProbe helps make sure enough tissue is removed during a lumpectomy. A lumpectomy is the removal of the tumor and some of the surrounding tissue, called a margin, during an operation. Currently, surgeons often have to wait one or two weeks to find out if the tissue around the tumor that was removed during surgery contains cancer cells. Because of this, up to 40% of women who have had a lumpectomy need to have more surgeries to remove this additional cancerous tissue.
Using a specialized 21-gene test of a breast tumor’s genes, researchers found that the result, called a Recurrence Score (RS), predicted the prognosis (chance of recovery) for patients with estrogen-receptor positive breast cancer that has spread to the axillary (underarm) lymph nodes. Previous studies have shown that these 21 genes help predict the risk of recurrence (cancer that comes back after treatment) and the risk of death from cancer for women with breast cancer that has not spread to the axillary lymph nodes.
A new simulation study indicates that women with stage II breast cancer who have a high risk of the cancer remaining in their axillary (underarm) lymph nodes after treatment, called residual nodal disease, may benefit from having these lymph nodes removed in a procedure called an axillary lymph node dissection. Women who have more cancerous lymph nodes in the underarm generally have a higher risk of residual nodal disease. Cancer in this area is found through a sentinel lymph node biopsy. A sentinel lymph node biopsy is the removal of one or a few lymph nodes in the underarm to look for cancer cells. If cancer cells are found, additional treatment may be needed.