ON THIS PAGE: You will find a list of common tests, procedures, and scans that doctors use to find the cause of a medical problem. Use the menu to see other pages.
Doctors use many tests to find, or diagnose, a tumor. They also do tests to learn if a tumor has spread to another part of the body from where it started. If this happens, it is called metastasis. For example, imaging tests can show if the tumor has spread. Imaging tests show pictures of the inside of the body. Doctors may also do tests to learn which treatments could work best.
For most tumor types, a biopsy is the only sure way for the doctor to know if an area of the body has a tumor. In a biopsy, the doctor takes a small sample of tissue for testing in a laboratory. If a biopsy is not possible, the doctor may suggest other tests that will help make a diagnosis.
This section describes options for diagnosing a CNS tumor. Not all tests listed below will be used for every child. Your child’s doctor may consider these factors when choosing a diagnostic test:
The type of tumor suspected
Your child’s signs and symptoms
Your child’s age and general health
The results of earlier medical tests
In addition to a physical examination, the following tests may be used to diagnose a CNS tumor:
Magnetic resonance imaging (MRI). This is the primary test used to find a brain tumor and plan treatment. An MRI uses magnetic fields, not x-rays, to produce detailed images of the body. A special dye called a contrast medium is given before the scan to create a clearer picture. This dye can be injected into a patient’s vein or given as a pill or liquid to swallow.
Computed tomography (CT or CAT) scan. A CT scan takes pictures of the inside of the body using x-rays taken from different angles. A computer combines these pictures into a detailed, 3-dimensional image that shows any abnormalities or tumors. A CT scan can be used to measure the tumor’s size. Sometimes, a special dye called a contrast medium is given before the scan to provide better detail on the image. This dye can be injected into a patient’s vein or given as a pill or liquid to swallow. Although MRI (see above) is the preferred test, a CT scan may be an option for diagnosing a brain tumor.
Biopsy. A biopsy for a CNS tumor is usually done with surgery to remove a small amount of tissue for examination under a microscope. Other tests can suggest that a tumor is present, but only a biopsy can make a definite diagnosis. A pathologist then analyzes the sample(s). A pathologist is a doctor who specializes in interpreting laboratory tests and evaluating cells, tissues, and organs to diagnose disease. The type of biopsy performed depends on the location of the tumor.
Molecular testing of the tumor. Your doctor may recommend running laboratory tests on a tumor to identify specific genes, proteins, and other factors unique to the tumor. Results of these tests may help determine your child's treatment options. This is not currently done for all types of childhood CNS tumors but may be done for some tumor types and in clinical trials (see Latest Research).
After diagnostic tests are done, your child’s doctor will review all of the results with you. If the diagnosis is a CNS tumor, these results also help the doctor describe the tumor. This is called staging and grading.
The next section in this guide is Stages and Grades. It explains the system doctors use to describe the extent of the disease. Use the menu to choose a different section to read in this guide.