Lymphoma - Hodgkin - Childhood: Latest Research

Approved by the Cancer.Net Editorial Board, 12/2018

ON THIS PAGE: You will read about the scientific research being done to learn more about this type of cancer and how to treat it. Use the menu to see other pages.

Doctors are working to learn more about Hodgkin lymphoma, ways to prevent it, how to best treat it, and how to provide the best care to children and adolescents diagnosed with this disease. The following areas of research may include new options for patients through clinical trials. Always talk with your child’s doctor about the best diagnostic and treatment options for your child.

  • New drugs. To reduce side effects and improve the effectiveness of treatment, it is important for researchers to find new drugs, as well as new combinations of current drugs.

  • Targeted therapy. Targeted therapy is a treatment that targets specific genes, proteins, or the tissue environment that contributes to cancer growth and survival. As mentioned in Types of Treatment, recent studies are evaluating antibodies—such as brentuximab vedotin (SGN-35)—directed against proteins on the Hodgkin lymphoma cells. Learn more about the basics of targeted treatments.

  • ALLO stem cell transplantation. As explained in the Types of Treatment section, stem cell/bone marrow transplantation is sometimes used to treat Hodgkin lymphoma. Doctors are researching increasing the use of transplantation, including ALLO transplantation using donor blood stem cells to replace the patient’s bone marrow (called allogeneic transplantation).

  • Personalized treatments. The major goal of Hodgkin lymphoma research is to improve treatment effectiveness while reducing long-term side effects. Early response of the disease to a specific treatment is being studied as a method to tailor therapy to the individual. Shorter, more intensive regimens may improve effectiveness. It is important that researchers learn which patients need radiation therapy and which patients may be cured without the long-term side effects of radiation exposure.

  • Palliative care/supportive care. Clinical trials are underway to find better ways of reducing symptoms and side effects of current Hodgkin lymphoma treatments in order to improve comfort and quality of life for patients.

Looking for More about Latest Research?

If you would like additional information about the latest areas of research regarding Hodgkin lymphoma, explore these related items that take you outside of this guide:

The next section in this guide is Coping with Treatment. It offers some guidance in how to cope with the physical, emotional, social, and financial changes that cancer and its treatment can bring. Use the menu to choose a different section to read in this guide.