ON THIS PAGE: You will find some basic information about mesothelioma and the parts of the body it may affect. This is the first page of Cancer.Net’s Guide to Mesothelioma. Use the menu to see other pages. Think of that menu as a roadmap for this complete guide.
Cancer begins when healthy cells change and grow out of control, forming a mass called a tumor. A tumor can be cancerous or benign. A cancerous tumor is malignant, meaning it can grow and spread to other parts of the body. A benign tumor means the tumor can grow but will not spread.
Mesothelioma is a rare cancer that begins in the lining of different internal organs of the body.
Approximately 75% to 80% of mesotheliomas begin in the lining surrounding the lungs. This is called pleural mesothelioma. Pleural mesothelioma begins in the chest cavity. It does not start in the lungs and it is often incorrectly called a lung cancer.
Peritoneal mesothelioma begins in the tissue surrounding the abdominal area, called the peritoneum. About 8% of mesotheliomas are peritoneal mesothelioma.
Rare types of mesothelioma can also begin in the lining around the heart, called the pericardium, or in the lining around the testicles, called the tunica vaginalis.
Types of mesothelioma
There are 3 main types of mesothelioma:
Epithelioid type. About 70% of people diagnosed with mesothelioma have the epithelioid type. Epithelioid mesothelioma may grow slower and chemotherapy often works better for this type.
Sarcomatoid type. Between 7% to 15% of people diagnosed with mesothelioma have the sarcomatoid type. Sarcomatoid mesothelioma may be more resistant to treatment compared with the other 2 types of mesothelioma. Standard chemotherapy often does not work well for this type of mesothelioma.
Mixed, or biphasic, type. Between 10% to 20% of people diagnosed with mesothelioma have the mixed type. The term “mixed” or “biphasic” means that the cancer contains both epithelioid and sarcomatoid types. Treatment does not work as well for this type when compared with the epithelioid type. However, treatment for this type often works better than for the sarcomatoid type.
The next section in this guide is Statistics. It helps explain the number of people who are diagnosed with mesothelioma and general survival rates. Use the menu to choose a different section to read in this guide.