ON THIS PAGE: You will learn more about clinical trials, which are the main way that new medical approaches are studied to see how well they work. Use the menu to see other pages.
What are clinical trials?
Doctors and scientists are always looking for better ways to care for people with uterine cancer. To make scientific advances, doctors create research studies involving volunteers, called clinical trials. Every drug that is now approved by the U.S. Food and Drug Administration (FDA) was tested in clinical trials.
Clinical trials are used for all types and stages of uterine cancer. Many focus on new treatments to learn if a new treatment is safe, effective, and possibly better than the existing treatments. These types of studies evaluate new drugs, different combinations of treatments, new approaches to radiation therapy or surgery, and new methods of treatment.
People who participate in clinical trials can be some of the first to get a treatment before it is available to the public. There are some risks with a clinical trial, including possible side effects and the chance that the new treatment may not work. Clinical trials may also be unavailable in certain locations or may have extensive exclusion criteria. People are encouraged to talk with their health care team about the pros and cons of joining a specific study.
Some clinical trials study new ways to relieve symptoms and side effects during treatment. Others study ways to manage the late effects that may happen a long time after treatment. Talk with your doctor about clinical trials for symptoms and side effects.
Deciding to join a clinical trial
People decide to participate in clinical trials for many reasons. For some, a clinical trial is the best treatment option available. Because standard treatments are not perfect, patients are often willing to face the added uncertainty of a clinical trial in the hope of a better result. Others volunteer for clinical trials because they know that these studies offer a way to contribute to the progress in treating uterine cancer. Even if they do not benefit directly from the clinical trial, their participation may yield future benefits for people with uterine cancer.
Insurance coverage and the costs of clinical trials differ by location and by study. Clinical trials may not be available in all locations, so travel is often a component of participation. In some programs, some of the expenses from participating in the clinical trial are reimbursed. In others, they are not. It is important to talk with the research team and your insurance company before starting treatment to learn if and how your participation in a clinical trial will be covered. Learn more about health insurance coverage of clinical trials.
Sometimes people have concerns that they might not receive active treatment in a clinical trial but instead receive a placebo or a “sugar pill.” When used, placebos are usually combined with standard treatment in most cancer clinical trials. Study participants will always be told when a placebo is used in a study. Find out more about placebos in cancer clinical trials.
Patient safety and informed consent
To join a clinical trial, patients must participate in a process known as informed consent. During informed consent, the doctor should:
Describe all of the treatment options so that the patient understands how the new treatment differs from the standard treatment.
List all of the risks of the new treatment, which may or may not be different from the risks of standard treatment.
Explain what will be required of each person while participating in the clinical trial, including the number of doctor visits, tests, and the schedule of treatment.
Describe the purposes of the clinical trial and what researchers are trying to learn.
Clinical trials have certain rules called “eligibility criteria” that help structure the research and keep patients safe. Patients must meet these criteria in order to participate in the study. You and the research team will carefully review these criteria together. You will need to meet all of the eligibility criteria in order to participate in a clinical trial. Learn more about eligibility criteria in clinical trials.
People who participate in a clinical trial may stop participating at any time for personal or medical reasons. This may include that the new treatment is not working or there are serious side effects. Clinical trials are closely monitored by experts who watch for any problems with each study. It is important that people participating in a clinical trial talk with their doctor and researchers about who will be providing their treatment and care during the clinical trial, after the clinical trial ends, and/or if they choose to leave the clinical trial before it ends.
Finding a clinical trial
Research through clinical trials is ongoing for all types of cancer. For specific topics being studied for uterine cancer, learn more in the Latest Research section.
Cancer.Net offers more information about cancer clinical trials in other areas of the website, including a complete section on clinical trials and places to search for clinical trials for a specific type of cancer.
There are many resources and services to help you search for clinical trials for uterine cancer, including the following services. Please note that these links will take you to separate, independent websites:
ClinicalTrials.gov. This U.S. government database lists publicly and privately supported clinical trials.
World Health Organization (WHO) International Clinical Trials Registry Platform. The WHO coordinates health matters within the United Nations. This search portal gathers clinical trial information from many countries’ registries.
Read more about the basics of clinical trials matching services.
In addition, you can find a free video-based educational program about cancer clinical trials in another section of this website.
The next section in this guide is Latest Research. It explains areas of scientific research for uterine cancer. Use the menu to choose a different section to read in this guide.