Oncologist-approved cancer information from the American Society of Clinical Oncology
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Mastocytosis

This section has been reviewed and approved by the Cancer.Net Editorial Board, 4/2013
Risk Factors

ON THIS PAGE: You will find out more about what factors increase the chance of developing this disorder. To see other pages in this guide, use the colored boxes on the right side of your screen, or click “Next” at the bottom.

A risk factor is anything that increases a person’s chance of developing a disease. Although risk factors often influence the development of mastocytosis, most do not directly cause the disorder. Some people with several risk factors never develop mastocytosis, while others with no known risk factors do. However, knowing your risk factors and talking about them with your doctor may help you make more informed lifestyle and health care choices.

The following factors may raise a person’s risk of developing mastocytosis:

Age. Most often, cutaneous mastocytosis begins during infancy and early childhood. The risk of developing mastocytosis also increases during middle age.

C-kit receptor mutation. The c-kit receptor is a protein on the surface of some cells that binds to stem cell factor (a substance that causes certain types of cells to grow). A mutation of c-kit may cause some types of mastocytosis.

Choose “Next” (below, right) to continue reading this guide to learn about what symptoms this disorder can cause. Or, use the colored boxes located on the right side of your screen to visit any section.

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