Cancer is relatively rare in children. Most cancers (98%) develop in adults, especially in people past middle age. About one out of every six adults will develop cancer during his or her lifetime, while one in 300 boys and one in 333 girls will develop cancer before the age of 20.
At the same time, however, there is a lot of research going on to discover new treatments for childhood cancer. This ongoing research has greatly improved the overall survival rate for children with cancer, which is now approximately 80%.
What is childhood cancer?
Cancer begins when normal cells change and grow uncontrollably. In most types of cancer, these cells form a mass called a tumor. A tumor can be benign (noncancerous) or malignant (cancerous, meaning it can spread to other parts of the body). In leukemia, a cancer of the blood that starts in the bone marrow, these abnormal cells rarely form a solid tumor, but instead crowd out other types of cells in the bone marrow. This prevents the production of normal red blood cells, other white blood cells, and platelets (the part of the blood needed for clotting).
Cancer in children most often forms in the parts of their bodies that are still growing and changing, such as their blood system, brain and nervous system, and kidneys. Most of the time, there is no known cause for childhood cancers. They may behave very differently from adult cancers.
Types of childhood cancer
Childhood cancer is a general term used to describe a range of cancer types and noncancerous tumors found in children. Childhood cancer may also be called pediatric cancer. Below are the most common types of cancer in children under 15 years old. For more information on each type, select a name below.
- Leukemia (accounts for about 34% of childhood cancer cases)
- Brain and central nervous system (CNS) tumors (27%), including tumors of the spinal cord
- Neuroblastoma (7%), a tumor of immature nerve cells that often starts in the adrenal glands, which are located on top of the kidneys and are part of the body’s endocrine (hormonal) system
- Wilms Tumor (5%), a type of kidney tumor
- Non-Hodgkin lymphoma (4%) and Hodgkin lymphoma (4%), cancers that begin in the lymph system
- Rhabdomyosarcoma (3%), a type of tumor that begins in the striated muscle, which are the skeletal voluntary muscles that people can control. Other, rare soft tissue sarcomas also occur.
- Retinoblastoma (3%), an eye tumor
- Osteosarcoma (3%) and Ewing sarcoma (1%), tumors that begin in the bone
- Germ cell tumors, rare tumors that begin in the testicles in boys and ovaries in girls. Even more rarely, this tumor can begin in other places in the body, including the brain.
- Pleuropulmonary blastoma, a rare lung cancer that begins in the chest
- Hepatoblastoma and hepatocellular carcinoma, which are liver tumors
Cancer in teenagers and young adults
There is an increasing amount of research regarding cancer in children diagnosed after the age of 14. As these children are starting to enter young adulthood, they may have unique medical, social, and emotional needs that are different from younger children with cancer. They are part of a group often called adolescents and young adults (AYA).
Most often, teenagers and young adults with cancer should be treated at a pediatric oncology center or at a center where medical oncologists (doctors who treat cancer with medication) and pediatric oncologists (doctors who treat children with cancer) work together to plan treatment. This will ensure that they receive the newest treatments and are cared for by a team of doctors who are familiar with these diseases. This is especially important for teenagers who have lymphoma, leukemia, and bone tumors, since treatment by specialists familiar with these diseases has been shown to improve survival.
Within the AYA group, there are also patients who have cancers most commonly found in adults, such as melanoma, testicular cancer, and ovarian cancer. Teenagers with these cancers may receive treatments that are similar to adults, but they also need to receive age-appropriate support for their social and emotional needs. In either the pediatric or adult care centers, age-appropriate information and support is very important for children and teens.
Below are the most common types of cancer in teenagers, ages 15 to 19. For more information on each type, select a name below.
Find out more about basic cancer terms used in this section.
Looking for More of an Overview?
If you would like additional introductory information, explore the following item on Cancer.Net:
- ASCO Answers Fact Sheet: Read a one-page fact sheet (available in PDF) that offers an easy-to-print introduction for several types of childhood cancer listed above.
- Cancer.Net Patient Education Videos: View short videos led by an ASCO expert in this type of cancer that provide basic information about childhood cancer treatment, areas of research, and survivorship.
Or, choose “Next” (below, right) to continue reading this detailed section. To select a specific topic within this section, use the icon panel located on the right side of your screen.
Last Updated: February 08, 2012
