About the lymph system
The lymph system is made up of thin tubes that branch out to all parts of the body. The lymph system carries lymph, a colorless fluid containing lymphocytes (white blood cells). Lymphocytes fight germs in the body. B-lymphocytes (also called B cells) make antibodies to fight bacteria, and T-lymphocytes (also called T cells) kill viruses and foreign cells and trigger the B cells to make antibodies.
Groups of tiny, bean-shaped organs called lymph nodes are located throughout the body at different sites in the lymph system. The most groupings are found in the abdomen, groin, pelvis, underarms, and neck. Other parts of the lymph system include the spleen, which makes lymphocytes and filters blood; the thymus, an organ under the breastbone; the tonsils, located in the throat; and the bone marrow, the spongy red tissue inside bones that produces white blood cells, red blood cells, and platelets (cells that help the blood clot).
About non-Hodgkin lymphoma
Lymphoma begins when cells in the lymph system change and grow uncontrollably, which may form a tumor. Hodgkin lymphoma is a specific type of lymphoma that is covered in another section of this website. Non-Hodgkin lymphoma (NHL) is a term that refers to many types of cancer of the lymph system, which can have different symptoms and signs, physical findings, and treatment strategies.
Because lymph tissue is found in so many parts of the body, NHL can start almost anywhere and can spread to almost any organ in the body. It most often begins in the lymph nodes, liver, spleen, or bone marrow, but it can also involve the stomach, intestines, skin, thyroid gland, brain, or any other part of the body.
It is very important to know which type and subtype has been diagnosed because the type and subtype help doctors determine the best treatment and a patient’s chance of recovery. Specific information can be found in Subtypes of NHL.
This section covers NHL in adults. Learn more about childhood NHL.
Find out more about basic cancer terms used in this section.
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Last Updated: July 27, 2011
