Lymphoma - Non-Hodgkin: Statistics

Approved by the Cancer.Net Editorial Board, 01/2021

ON THIS PAGE: You will find information about the number of people who are diagnosed with NHL each year. You will also read general information on surviving the disease. Remember, survival rates depend on several factors. Use the menu to see other pages.

NHL is the seventh most common cancer in men and the sixth most common cancer in women. The disease accounts for 4% of all cancers in the United States.

This year, an estimated 81,560 people (45,630 men and 35,930 women) in the United States will be diagnosed with NHL. The disease can be diagnosed at any age, including in children, teens, and young adults. However, NHL risk increases with age. Over half of patients are age 65 or older when diagnosed. About 4,600 people ages 15 to 39 will be diagnosed with NHL this year.

It is estimated that 20,720 deaths (12,170 men and 8,550 women) from this disease will occur this year. It is the ninth most common cause of cancer death among both men and women. The survival rate has been improving since 1997, thanks to treatment advances. From 2009 to 2018, the death rate decreased by 2% annually.

The 5-year survival rate tells you what percent of people live at least 5 years after the cancer is found. Percent means how many out of 100. The overall 5-year survival rate for people with NHL is 73%.  

For stage I NHL, the 5-year survival rate is more than 83%. For stage II the 5-year survival rate is close to 76% and for stage III it is more than 70%. For stage IV NHL, the 5-year survival rate is around 63%. These survival rates vary depending on the cancer’s stage and subtype.

It is important to remember that statistics on the survival rates for people with NHL are an estimate. The estimate comes from annual data based on the number of people with this cancer in the United States. Also, experts measure the survival statistics every 5 years. So the estimate may not show the results of better diagnosis or treatment available for less than 5 years. Talk with your doctor if you have any questions about this information. Learn more about understanding statistics.

Statistics adapted from the American Cancer Society’s (ACS) publications, Cancer Facts & Figures 2021 and Cancer Facts & Figures 2020, the ACS website, and the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) Program (sources accessed January 2021).

The next section in this guide is Medical Illustrations. It offers drawings of body parts often affected by NHL. Use the menu to choose a different section to read in this guide.