Lymphoma - Non-Hodgkin: Statistics

Approved by the Cancer.Net Editorial Board, 02/2022

ON THIS PAGE: You will find information about the number of people who are diagnosed with non-Hodgkin lymphoma (NHL) each year. You will also read general information on surviving the disease. Remember, survival rates depend on several factors. Use the menu to see other pages.

NHL is the seventh most common cancer in men and the sixth most common cancer in women. The disease accounts for 4% of all cancers in the United States.

This year, an estimated 80,470 people (44,120 men and 36,350 women) in the United States will be diagnosed with NHL. After decades of increasing, the number of people diagnosed with the disease began dropping. From 2009 to 2018, incidence rates of NHL decreased by 0.4% each year. The disease can be diagnosed at any age, including in children, teens, and young adults. However, NHL risk increases with age. Over half of patients are 65 or older when they are diagnosed. Worldwide, an estimated 544,352 people were diagnosed with NHL in 2020.

It is estimated that 20,250 deaths (11,700 men and 8,550 women) from this disease will occur in the United States this year. It is the ninth most common cause of cancer death among both men and women. The survival rate has been improving since 1997, thanks to treatment advances. From 2010 to 2019, the death rate decreased by slightly more than 2% every year. In 2020, an estimated 259,793 people worldwide died from NHL.

The 5-year survival rate tells you what percent of people live at least 5 years after the cancer is found. Percent means how many out of 100. The overall 5-year survival rate for people with NHL in the United States is 73%.  

For stage I NHL, the 5-year survival rate is more than 84%. For stage II the 5-year survival rate is 77%, and for stage III it is more than 71%. For stage IV NHL, the 5-year survival rate is almost 64%. These survival rates vary depending on the cancer’s stage and subtype.

It is important to remember that statistics on the survival rates for people with NHL are an estimate. The estimate comes from annual data based on the number of people with this cancer in the United States. The survival rates for NHL on this page are based on people diagnosed between 2011 and 2017. Also, experts measure the survival statistics every 5 years. This means the estimate may not reflect the results of advancements in how NHL is diagnosed or treated in recent years. Talk with your doctor if you have any questions about this information. Learn more about understanding statistics.

Statistics adapted from the American Cancer Society’s (ACS) publications, Cancer Facts & Figures 2022 and Cancer Facts & Figures 2020, the ACS website, the International Agency for Research on Cancer website, and the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) Program. (All sources accessed January 2022.)

The next section in this guide is Medical Illustrations. It offers drawings of the parts of the lymphatic system. Use the menu to choose a different section to read in this guide.